Xinyi Chen Selected Research

Alzheimer Disease (Alzheimer's Disease)

12/2022	Design, synthesis and biological evaluation of pyranocarbazole derivatives against Alzheimer's disease, with antioxidant, neuroprotective and cognition enhancing properties.
1/2022	Acrolein, an endogenous aldehyde induces synaptic dysfunction in vitro and in vivo: Involvement of RhoA/ROCK2 pathway.
2/2021	Claulansine F-Donepezil Hybrids as Anti-Alzheimer's Disease Agents with Cholinergic, Free-Radical Scavenging, and Neuroprotective Activities.

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Xinyi Chen Research Topics

Disease

55	Neoplasms (Cancer) 03/2024 - 04/2003
17	Cataract (Cataracts) 04/2024 - 01/2016
10	Inflammation (Inflammations) 08/2023 - 01/2014
7	Neoplasm Metastasis (Metastasis) 01/2024 - 01/2020
7	Infections 01/2022 - 01/2020
6	Breast Neoplasms (Breast Cancer) 11/2023 - 10/2011
5	Hepatocellular Carcinoma (Hepatoma) 01/2024 - 12/2018
5	Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune) 02/2023 - 09/2016
4	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2024 - 06/2019
4	Bullous Pemphigoid (Pemphigoid) 12/2023 - 01/2020
4	Tuberculosis (Tuberculoses) 07/2023 - 01/2021
4	Colorectal Neoplasms (Colorectal Cancer) 11/2022 - 06/2015
4	Rupture 01/2022 - 01/2017
3	Sepsis (Septicemia) 05/2024 - 01/2021
3	Ischemic Stroke 01/2024 - 01/2021
3	Carcinogenesis 01/2024 - 08/2023
3	Glioma (Gliomas) 08/2023 - 01/2021
3	Fibrosis (Cirrhosis) 06/2023 - 09/2021
3	Alzheimer Disease (Alzheimer's Disease) 12/2022 - 02/2021
3	Hemorrhage 04/2021 - 06/2018
3	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 01/2021 - 01/2020
3	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2019 - 07/2015
3	Myocardial Infarction 01/2014 - 10/2006
2	Stomach Neoplasms (Stomach Cancer) 04/2024 - 06/2019
2	Cardiovascular Diseases (Cardiovascular Disease) 03/2024 - 01/2014
2	Disease Progression 01/2024 - 10/2016
2	Brain Edema (Cerebral Edema) 01/2024 - 01/2022
2	Stroke (Strokes) 01/2024 - 01/2024
2	Skin Diseases (Skin Disease) 12/2023 - 01/2020
2	Chronic Obstructive Pulmonary Disease (COPD) 11/2023 - 01/2021
2	Colonic Neoplasms (Colon Cancer) 11/2023 - 01/2020
2	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2023 - 01/2022
2	Corneal Edema 05/2022 - 01/2017
2	COVID-19 01/2022 - 01/2020
2	Liver Neoplasms (Liver Cancer) 12/2020 - 01/2019
2	Thrombocytopenia (Thrombopenia) 06/2019 - 08/2018
2	Body Weight (Weight, Body) 01/2019 - 10/2006
2	Carcinoma (Carcinomatosis) 05/2017 - 05/2012
2	Astigmatism 01/2017 - 01/2016
2	Endophthalmitis (Ophthalmia) 01/2017 - 01/2017
1	Sebaceous of Jadassohn Nevus 04/2024

Drug/Important Bio-Agent (IBA)

10	Proteins (Proteins, Gene)FDA Link 03/2024 - 03/2019
9	Biomarkers (Surrogate Marker)IBA 04/2024 - 11/2020
7	CytokinesIBA 12/2023 - 04/2019
5	Inosine Triphosphate (ITP)IBA 02/2023 - 09/2016
5	Therapeutic UsesIBA 01/2021 - 10/2011
4	Messenger RNA (mRNA)IBA 01/2024 - 01/2022
4	RNA (Ribonucleic Acid)IBA 01/2024 - 01/2022
4	MicroRNAs (MicroRNA)IBA 11/2023 - 07/2013
4	Rifampin (Rifampicin)FDA LinkGeneric 07/2023 - 01/2021
4	Capsules (Microcapsules)IBA 07/2023 - 01/2017
3	Carbapenems (Carbapenem Antibiotics)IBA 05/2024 - 01/2022
3	Anti-Bacterial Agents (Antibiotics)IBA 05/2024 - 01/2017
3	DNA (Deoxyribonucleic Acid)IBA 11/2023 - 01/2021
3	CateninsIBA 11/2022 - 10/2011
3	Small Interfering RNA (siRNA)IBA 01/2022 - 01/2017
2	Sirolimus (Rapamycin)FDA Link 03/2024 - 06/2023
2	Antineoplastic Agents (Antineoplastics)IBA 03/2024 - 01/2019
2	Immune Checkpoint InhibitorsIBA 01/2024 - 01/2022
2	Small Cytoplasmic RNAIBA 01/2024 - 11/2023
2	Interleukin-4 (Interleukin 4)IBA 12/2023 - 01/2023
2	AutoantibodiesIBA 12/2023 - 01/2021
2	CholesterolIBA 10/2023 - 01/2022
2	Hemoglobins (Hemoglobin)IBA 10/2023 - 01/2020
2	LipidsIBA 10/2023 - 12/2020
2	AntigensIBA 10/2023 - 12/2022
2	CollagenIBA 06/2023 - 06/2022
2	LipopolysaccharidesIBA 01/2023 - 01/2019
2	InterferonsIBA 01/2023 - 01/2022
2	Indicators and Reagents (Reagents)IBA 01/2023 - 01/2007
2	Chimeric Antigen ReceptorsIBA 12/2022 - 08/2022
2	TeaIBA 06/2022 - 05/2012
2	LigandsIBA 01/2022 - 01/2016
2	AntibodiesIBA 01/2022 - 01/2021
2	AcidsIBA 01/2021 - 12/2020
2	Histone Deacetylases (Histone Deacetylase)IBA 01/2021 - 08/2020
2	n-pentanoic acid (valeric acid)IBA 01/2021 - 12/2020
2	Histone Deacetylase InhibitorsIBA 01/2021 - 12/2020
2	Paclitaxel (Taxol)FDA LinkGeneric 01/2021 - 01/2015
2	Caspase 3 (Caspase-3)IBA 01/2021 - 01/2019
2	Valeriana extractIBA 01/2021 - 12/2020
2	Toll-Like Receptor 4IBA 01/2021 - 01/2019
2	Indomethacin (Indometacin)FDA LinkGeneric 09/2020 - 01/2020
2	Interleukin-6 (Interleukin 6)IBA 01/2020 - 10/2006
2	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2020 - 10/2006
2	Peptides (Polypeptides)IBA 01/2014 - 01/2013
1	secukinumabIBA 04/2024

Therapy/Procedure

27	Therapeutics 03/2024 - 01/2019
10	Phacoemulsification 04/2024 - 01/2016
9	Lasers (Laser) 04/2024 - 01/2016
7	Immunotherapy 04/2024 - 01/2023
6	Chinese Traditional Medicine (Traditional Chinese Medicine) 01/2023 - 06/2018
5	Drug Therapy (Chemotherapy) 01/2023 - 10/2016
4	Intraocular Lenses (Intraocular Lens) 06/2023 - 01/2019
3	Thrombectomy 01/2024 - 01/2022
2	Stents 03/2024 - 01/2014
2	Radiotherapy 06/2023 - 05/2017
2	Refractive Surgical Procedures 11/2021 - 01/2020
2	Capsulorhexis 01/2019 - 01/2016
1	Artificial Respiration (Mechanical Ventilation) 05/2024